RNAi: Stopping the Power of Misfolded Proteins

(DGIwire) – The idea of targeted, personalized medicine has been a dream for decades—and it is now becoming a reality thanks to advances in genetics. As recently reported in an article on the website of the American Society of Mechanical Engineers (ASME), a large part of this revolution is being driven by advances in understanding […]

CAR-T Cell Therapy: Just the First Step for Immuno-Oncology

(DGIwire) – The U.S. Food and Drug Administration’s recent approval of Novartis’ gene therapy—for the treatment of children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia—represents a watershed moment for healthcare. As Healio recently reported, Kymriah provides unprecedented benefits to poor prognosis patients who have exhausted all other treatment options. What makes […]

Self-Delivering RNAi Compounds: A Unique Therapy for a Wide Range of Diseases

(DGIwire) – When several biotech companies are pursuing a common goal, the company that eventually winds up in front can usually point to a unique innovation for its success. In the hot research area of RNA interference (RNAi), this secret sauce might be found in the form of something called “self-delivering RNAi” (sd-rxRNA®)—and its innovator, […]

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