3 Challenges Facing Immunotherapy and How RNAi Might Help

(DGwire) – The battle against solid tumors in cancer immunotherapy is engaging some of the brightest minds in medicine. While predictions suggest the immunotherapy market will be worth about $25 billion by 2030, there are still some hurdles to overcome in the effort to improve treatment options, including: Boosting the immune system to fight: As […]

RNAi: Paving the Way to a New Class of Treatments

(DGIwire) – These are exciting times for gene therapy. As Business Insider recently reported, a biopharmaceutical company announced positive results from a late-stage clinical study of a drug for a rare nerve disorder, familial amyloid polyneuropathy. This drug, notes a report in STAT, harnesses a phenomenon called RNA interference (RNAi). This is a naturally occurring […]

CAR-T Cell Therapy: Just the First Step for Immuno-Oncology

(DGIwire) – The U.S. Food and Drug Administration’s recent approval of Novartis’ gene therapy—for the treatment of children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia—represents a watershed moment for healthcare. As Healio recently reported, Kymriah provides unprecedented benefits to poor prognosis patients who have exhausted all other treatment options. What makes […]

Hypertrophic Scars: What Are They?

(DGIwire) – Not all scars are created equal. While always unsightly, a certain type—known as hypertrophic scars—can be especially bothersome, both physically and psychologically, for those who have them. But what are they, exactly? According to Medscape, hypertrophic scars are characterized by abnormally red, itchy, raised fibrous lesions that typically do not expand beyond the […]

Delivering Another Option in Immunotherapy Treatment

(DGIwire) – Within the realm of cancer care, immunotherapy is increasingly occupying the spotlight. And with good reason: as many recent headlines show, this form of therapy holds great promise for improved treatment of a wide variety of cancers. There exist several approaches to immunotherapy, each with its specific strengths. One fascinating approach to immunotherapy, […]

RNA Interference: Nobel-Winning Science Coming to Fruition

(DGIwire) – When Craig C. Mello and Andrew Z. Fire were jointly awarded the Nobel Prize in Physiology and Medicine in 2006, the phenomenon for which they were honored—RNA interference (RNAi)—had already been making headlines for years since its initial discovery in 1998. RNAi is a naturally occurring process by which a particular “messenger RNA” […]

The Truth About HPV, Warts and All

(DGIwire) – The human papillomavirus (HPV) is the most common sexually transmitted infection in the U.S., reports the Centers for Disease Control and Prevention (CDC). At least half of sexually active men and women will acquire HPV in their lifetime, according to research published in the journal Sexually Transmitted Diseases. In addition, HPV is associated […]

Broccoli and Vision: A Surprising Connection

(DGIwire) – Carrots are supposedly beneficial for eyesight but—broccoli? Researchers from the Buck Institute for Research on Aging, located in Novato, CA, recently boosted the potency of a broccoli-related compound by 10 times and identified it as a possible treatment for age-related macular degeneration (AMD), a leading cause of vision loss affecting more than two […]

Age-Related Macular Degeneration: A ‘20/20 Vision’ for Better Care

(DGIwire) – What do actors Dabney Coleman, Roseanne Barr and Dame Judi Dench have in common? All three suffer from age-related macular degeneration (AMD), a condition that is the leading cause of vision loss, affecting more than 10 million Americans—more than cataracts and glaucoma combined, according to the American Macular Degeneration Foundation. AMD is a […]

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