An International Quest to Make Vaccines and Drugs More Accessible and Affordable

(DGIwire) – In recent years, monoclonal antibodies—or “mAbs” for short—have emerged as preferred therapeutic candidates for the treatment of a multitude of disorders and diseases. These include a broad range of cancers, autoimmune diseases and microbial infections. Traditionally, however, antibody treatment has been extremely costly and not widely affordable. Recently, an initiative of truly international […]

The Biggest Driver of High Drug Prices: Biologics

(DGIwire) – In 2017, biologic drugs represented two percent of all U.S. prescriptions but 37 percent of all drug spending, according to data from the IQVIA Institute. Furthermore, since 2014, biologics have accounted for nearly all the growth in drug spending: 93 percent of it. What accounts for these incredible figures? A recent article in […]

3 Things to Know About Biological Therapy for Cancer

(DGIwire) – For patients with cancer, biological therapies may be used to treat the cancer itself or the side effects of other cancer treatments, according to the National Cancer Institute (NCI). Many forms of biological therapies have been approved and others are still being studied in clinical trials. Here are three things to know about […]

Looking Beyond Mammals to Microbes for Tomorrow’s Drugs

(DGIwire) – In order to create the current generation of biologic drugs, manufacturers have largely depended on cell lines derived from mammals—specifically, the Chinese hamster ovary (CHO) cell. But as Mark Emalfarb, President and CEO of Dyadic International, wrote recently on, it may be time to move from mammals to microbes for the next […]

Is a Fungus Among Us the Key to Tomorrow’s Biologic Drugs?

(DGIwire) – If the word “fungus” stirs up nothing but unpleasant thoughts, it might be time to reconsider. Recall that a fungal organism was instrumental to the serendipitous discovery of the first true antibiotic, penicillin. In 1928, as notes, Sir Alexander Fleming returned from a two-week vacation to find that a mold had developed […]

Building Better Biologics: A Challenge for the Biopharma Industry

(DGIwire) – Biologic drugs are playing an increasingly greater role in the toolkit of healthcare providers in the 21st century. But as a recent article on noted, a variety of pressures are pushing the pharmaceutical industry toward more streamlined ways of manufacturing their products as demand for them grows. For example, biologic drug development […]